MIcrosimulation SCreening Analysis (MISCAN) Esophagus Cancer Model

Basic Model Attributes
Cancer siteEsophageal
Host institution Erasmus University Medical Center / University of Washington
Purpose The MISCAN/UW Esophagus adenocarcinoma (EAC) model is constructed for multiple purposes. First, we intend to gain better insight into the natural history of EAC, especially with regards to the process by which cancer develops from Barrett's Esophagus (BE). Secondly, the model will be used to identify the driving factors for the substantial increase in EAC incidence over the last several decades. The model will be able to inform investigators which factors could underlie plausible explanations for the period or birth cohort efforts observed in the BE and EAC increases. Finally, the model will be used in comparative effectiveness studies to calculate consequences of screening, surveillance and treatment strategies.
Contact Amir Omidvari (a.omidvari@erasmusmc.nl)