MISCAN-Lung (Erasmus)

MIcrosimulation SCreening Analysis (MISCAN) Lung Model

Basic Model Attributes
Cancer siteLung
Host institution Erasmus University Medical Center
Purpose The MISCAN-lung model was designed to simulate population trends in lung cancer (LC) for comprehensive surveillance of the disease, to relate past exposure to risk factors to (observed) LC incidence and mortality, and to estimate the impact of cancer-control interventions. MISCAN-lung employs the technique of stochastic microsimulation of life histories affected by risk factors. It includes the two-stage clonal expansion model for carcinogenesis and a detailed LC progression model; the latter is specifically intended for the evaluation of screenings. (ten Haaf, 2015, Cancer Epidemiology, Biomarkers & Prevention).
Contact Kevin ten Haaf (K.tenhaaf@erasmusmc.nl)