SimCRC (Minnesota/MGH)

Basic Model Attributes
Cancer siteColorectal
Host institution University Of Minnesota / MGH
Purpose The purpose of the SimCRC model is to address questions related to cancer control and prevention. The model has a natural history component that represents the adenoma-carcinoma process; parameters that describe that process were estimated by calibrating to observed data on adenoma prevalence and cancer incidence. To evaluate the impact of a screening program we allow for an underlying adenoma to be detected and removed - potentially interrupting the adenoma-carcinoma sequence - or a preclinical cancer to be detected at an earlier stage.
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