UW-Cervical (UWash)

Dynamic, compartmental, HPV 16 model

Basic Model Attributes
Cancer siteCervical
Host institution University of Washington
Purpose A dynamic compartmental model of HPV 16 infection and progression to cervical cancer (including LSIL and HSIL progression and regression). The model includes both men and women, sexual behavior, smoking, and vaccination strategies of varying coverage and duration as well as screening and treatment. This model was used to estimate the reduction of cervical cancer associated with varying assumptions of HPV 16 vaccine efficacy, duration, and population coverage. Comparative CC reductions from vaccinating men and women vs women only are evaluated.
Contact Ruanne Barnabas (rbarnaba@uw.edu)